Skip to content

Goals

📝 Research Goals

OpenProphetDB is an open research group focused on unlocking the potential of existing drugs to save patients with rare and complex diseases. We explore the following topics: constructing and integrating knowledge graph, multi-omics data, and deep learning models to understand the molecular mechanisms of human rare and complex diseases, or to predict new indications for known drugs through drug repurposing.

📚 Research Tasks

Rare and complex diseases, such as ME/CFS, Long Covid, ALS, etc.

🧑‍🔬 Curating BioMedical Knowledges and Omics Data

  • Curate multi-omics data and knowledge from public databases and literatures for Rare and complex diseases.

🕸️ Building BioMedical Knowledge Graph

  • Build a biomedical knowledge graph for drug repurposing and disease mechanism for Rare and complex diseases.

Knowledge Graph

🧮 Data Analysis and Modeling

  • Analyze multi-omics data for Rare and complex diseases.
  • Train deep learning models to integrate multi-omics data and knowledge graph to predict drugs and understand disease mechanisms for Rare and complex diseases.
Last update: 2025-04-23
Back to top