OpenProphetDB
An open research community dedicated to unlocking the therapeutic potential of existing drugs for patients with rare and complex diseases. We advance precision medicine through the integration of Electronic Health Records, Knowledge Graphs, Multi-Omics Data, and Deep Learning Models.
Our Mission
We focus on rare and complex diseases such as ME/CFS, Long Covid, ALS, and more, leveraging cutting-edge technologies to accelerate drug discovery and precision medicine.
Electronic Health Records
Integrate and analyze electronic health records to understand patient phenotypes, disease progression, and treatment outcomes for rare and complex diseases.
Multi-Omics Data Integration
Curate and analyze multi-omics data from public databases and literature for rare and complex diseases, enabling comprehensive molecular profiling and biomarker discovery.
Biomedical Knowledge Graph
Build comprehensive biomedical knowledge graphs for drug repurposing and disease mechanism understanding, connecting genes, drugs, diseases, and molecular pathways.
Deep Learning Models
Develop advanced AI models that integrate multi-omics data and knowledge graphs to predict drug candidates and understand disease mechanisms for rare and complex diseases.
Our Platforms & Tools
Open-source platforms and tools developed by our community for drug discovery, data analysis, and precision medicine research.
💊
Drug & Target
Comprehensive drug and target databases with advanced search and analysis tools for drug repurposing research.
Database Explore Database →📊
MultiOmics Data
Multi-omics data analysis platforms and quality control tools for comprehensive molecular profiling.
Analysis View Tools →🤖
MultiAgents
Multi-agent systems and AI tools for automated biomedical research and knowledge discovery.
AI Tools Explore AI Tools →15+
Team Members
20+
Publications
10+
Open Source Projects
5+
Online Platforms
Our Team
Meet the researchers and developers behind OpenProphetDB, working across prestigious institutions worldwide.
Team Members
Jingcheng Yang (杨竞成)
Post-doc Fellow
Harvard Medical School & MGH
Zihan Ran (冉子涵)
Post-doc Fellow
Harvard Medical School & MGH
Jun Shang (商骏)
Post-doc Fellow
Fudan University & FUSCC
Yechao Huang (黄业超)
Senior Scientist
BGI Genomics
Zhixing Zhu (朱之星)
Scientist
Shanghai Jiao Tong University
Jiaqi Weng (翁嘉绮)
Ph.D. Student
Zhejiang University of Technology
Xiang Li (李翔)
IT Manager
Liang Liu (刘梁)
Physician
Fudan University & ZS Hospital
Feng Zhu (朱枫)
Ph.D. Student
Fudan University
Penghao Xu (徐鹏昊)
Post-doc Fellow
Georgia Tech
Xiaofei Li (黎小飞)
Ph.D.
Guilin Medical University
Tianyuan Cheng (成天元)
Research Data Analyst
Johns Hopkins University
Wenjie Chen (陈文杰)
Post-doc Fellow
MD Anderson Cancer Center
Jinrong Ma (马金荣)
Scientist
Sanofi
Dongchang Qin (秦东昌)
Scientist
AbbVie
Jianming Wei (魏建铭)
Ph.D. Candidate
Utrecht University
Jingcheng Yang (杨竞成)
Post-doc Fellow
Harvard Medical School & MGH
Zihan Ran (冉子涵)
Post-doc Fellow
Harvard Medical School & MGH
Jun Shang (商骏)
Post-doc Fellow
Fudan University & FUSCC
Yechao Huang (黄业超)
Senior Scientist
BGI Genomics
Zhixing Zhu (朱之星)
Scientist
Shanghai Jiao Tong University
Jiaqi Weng (翁嘉绮)
Ph.D. Student
Zhejiang University of Technology
Xiang Li (李翔)
IT Manager
Liang Liu (刘梁)
Physician
Fudan University & ZS Hospital
Feng Zhu (朱枫)
Ph.D. Student
Fudan University
Penghao Xu (徐鹏昊)
Post-doc Fellow
Georgia Tech
Xiaofei Li (黎小飞)
Ph.D.
Guilin Medical University
Tianyuan Cheng (成天元)
Research Data Analyst
Johns Hopkins University
Wenjie Chen (陈文杰)
Post-doc Fellow
MD Anderson Cancer Center
Jinrong Ma (马金荣)
Scientist
Sanofi
Dongchang Qin (秦东昌)
Scientist
AbbVie
Jianming Wei (魏建铭)
Ph.D. Candidate
Utrecht University
Partner Institutions
Harvard University
Harvard Medical School
Massachusetts General Hospital
Fudan University
Georgia Institute of Technology
Shanghai Jiao Tong University
Zhongshan Hospital
Utrecht University
Heidelberg University
Guilin Medical University
AbbVie
Sanofi
Harvard University
Harvard Medical School
Massachusetts General Hospital
Fudan University
Georgia Institute of Technology
Shanghai Jiao Tong University
Zhongshan Hospital
Utrecht University
Heidelberg University
Guilin Medical University
AbbVie
Sanofi
Join Our Community
We are looking for partners who are highly motivated on drug repurposing to join the OpenProphetDB community. Let's work together to unlock the therapeutic potential of existing drugs for patients with rare and complex diseases.